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EIC of OJEMB, Harvard Medical School

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Using Mobile Health Technology to Inform the Clinical Management of Patients with Neurological Conditions


This lecture will review recent advances in the application of wearable and mhealth technologies to the clinical management of patients with neurological conditions such as Parkinson’s disease, stroke, and traumatic brain injury. We will show how relying on wearable and mhealth technologies as well as on machine learning-based algorithms, researchers have developed approaches suitable to derive accurate estimates of clinical scores from sensor data collected during the performance of functional movements. Examples provided during the lecture will include techniques to derive the severity of symptoms in patients with Parkinson’s disease as well as motor impairments and functional limitations in stroke and traumatic brain injury survivors. Furthermore, we will discuss how wearable and mhealth technologies can be used to collect kinematic and EMG data and derive data about the motor primitives underlying the generation of movement patterns thus improving our ability to assess motor learning. Finally, we will discuss how these technologies can transform the way clinical interventions are designed and implemented as they enable tracking individual responses to the prescribed therapy.


Paolo Bonato, Ph.D., serves as Director of the Motion Analysis Laboratory at Spaulding Rehabilitation Hospital, Boston MA. He is an Associate Professor in the Department of Physical Medicine and Rehabilitation at Harvard Medical School, an Adjunct Professor of Biomedical Engineering at the MGH Institute of Health Professions, an Associate Faculty Member at the Wyss Institute for Biologically Inspired Engineering, and an Adjunct Associate Professor at Boston University College of Health & Rehabilitation Sciences. He has held Adjunct Faculty positions at MIT, the University of Ireland Galway, and the University of Melbourne. His research work is focused on the development of rehabilitation technologies with special emphasis on wearable technology and robotics. Dr. Bonato served as the Founding Editor-in-Chief of Journal on NeuroEngineering and Rehabilitation and currently serves as Founding Editor-in-Chief of the IEEE Open Journal of Engineering in Medicine and Biology. He received the M.S. degree in electrical engineering from Politecnico di Torino, Turin, Italy in 1989 and the Ph.D. degree in biomedical engineering from Universita` di Roma “La Sapienza” in 1995.

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